Pharmacology S1.6: Structural Modifications and Drug Effects Pharmacology S1.6: Structural Modifications and Drug Effects Pharmacology S1.6: Structural Modifications and Drug Effects # 1. Structural Modification of Drugs 1.1. Structural Changes Influencing Pharmacokinetics (PK): Structural modification → alteration in physicochemical properties of the drug: Water/lipid solubility Drug-plasma protein binding Ionization Drug stability 1.2. Structural Changes Influencing…

Physiology Master’s Degree Review – Knowledge Compilation Physiology Master’s Degree Review – Knowledge Compilation Physiology Master’s Degree Review – Knowledge Compilation I. Reflexes Flexor reflex: Characteristics: Summation: Reflex intensity increases with repeated stimulation. Habituation: With continuous stimulation, the reflex gradually decreases and may disappear. Dependent on stimulation frequency: Higher stimulation frequency leads to stronger reflexes.…

3 Reproductive Multiple Choice Questions: Fertilization, Implantation and Development of the Egg 3 Reproductive Multiple Choice Questions: Fertilization, Implantation and Development of the Egg 3 Reproductive Multiple Choice Questions: Fertilization, Implantation and Development of the Egg This article includes 29 multiple-choice questions about fertilization, implantation, and the development of the egg, aiming to help you…

Fractures in Children Fractures in Children Fractures in Children Characteristics of Children’s Bones Compared to Adults: Thick articular cartilage: This makes X-ray images less clear. Thick periosteum: Helps bones heal quickly. High collagen content: Makes bones more prone to fractures. More cancellous bone: Results in simple fracture patterns. Growth plate: Allows for correction of bone…

Postpartum Knowledge: Common Quiz Questions Postpartum Knowledge: Common Quiz Questions Postpartum Knowledge: Common Quiz Questions This article focuses on knowledge related to the postpartum period, providing essential information about the physiological and anatomical changes that occur after childbirth. 1. Re-epithelialization of the uterine endometrium: – Begins 2 weeks after delivery. 2. Closure of the cervical…

Respiratory System Characteristics in Children Respiratory System Characteristics in Children Respiratory System Characteristics in Children The respiratory system of children has distinct characteristics compared to adults, which influence respiratory function and make them more vulnerable. 1. Airways: Nose: Nostrils and nasal passages are narrow, prone to nasal congestion, especially in infants under 6 months. Nasal…

Educational Psychology – Chapter 2: Individual Psychological Characteristics of Learners (1) Educational Psychology – Chapter 2: Individual Psychological Characteristics of Learners (1) Educational Psychology – Chapter 2: Individual Psychological Characteristics of Learners (1) # 1.1. Misconceptions about Individual Psychological Development Some notions about individual psychological development have been proven inaccurate, including: Predetermination Theory: This theory…

Mutation and Variation Mutation and Variation Mutation refers to changes in the genotype, specifically the sequence of base pairs in the DNA of an organism. Gene mutation is a type of mutation that directly affects the structure of a gene, altering the sequence of base pairs in the RNA structure of an organism. Point mutation…

Regulations on Drug and Drug Ingredient Registration and Circulation in Vietnam Regulations on Drug and Drug Ingredient Registration and Circulation in Vietnam Regulations on Drug and Drug Ingredient Registration and Circulation in Vietnam 1. Significance of Drug Registration Number The drug registration number is a crucial factor in ensuring efficacy and safety for users. It…

Article on Miscarriage: Article on Miscarriage: Article on Miscarriage: Miscarriage is a common condition that occurs when a pregnancy ends before the fetus can survive. Early miscarriages account for about 15% of pregnancies, with later miscarriages occurring at a lower rate. Causes of Miscarriage: Chromosomal abnormalities in the fetus: This is the most common cause,…