Hepatitis C: Understand, Treat Effectively

Chronic hepatitis C is a continuously progressing disease, often with few symptoms and silent progression. Most patients have no symptoms until liver complications appear.

The main cause of this progression is HCV core antigen.

Hepatitis C treatment is recommended for everyone, unless the patient has a short life expectancy.

People who need treatment:

• All patients with chronic hepatitis C infection (HCV RNA positive > 6 months)

• Regardless of genotype and degree of liver fibrosis

Contraindications for treatment with direct-acting antiviral (DAA) regimens:

• Children under 3 years old

• Pregnant women

• Do not use DAA with drugs that have undesirable interactions, serious side effects

Treatment principles:

• Hepatitis C should be treated early, especially in cases of:

• Liver fibrosis

• HIV/HCV infection/ injection drug use

• Women who want to become pregnant

• Choose a suitable DAA regimen based on:

• Degree of liver cirrhosis

• Comorbidities

• Drug interactions

• Accessibility of genotype testing (if the healthcare facility is unable to perform genotype testing, choose a regimen that is effective for all genotypes)

Hepatitis C treatment regimens:

• For adults over 18 years old, with no cirrhosis or compensated cirrhosis, first-time treatment: [Provide information on specific regimen].

• For adults over 18 years old, with decompensated cirrhosis and first-time treatment: [Provide information on specific regimen].

Note: Information about specific regimens should be updated from a specialist doctor to ensure safety and effectiveness of treatment.