Compilation of Questions About Cervical Cancer

Compilation of Questions About Cervical Cancer

Below are some questions and answers regarding cervical cancer:

Question 1:

Which of the following is NOT a cofactor for cervical cancer?

• A. Smoking

• B. Early sexual activity

• C. Multiple sexual partners

• D. Early menarche

• E. Impaired immunity

Answer: D

Question 2:

Cancer with clinical lesions confined to the cervix, the lesion size is < 4cm is classified in which stage?

• A. Ia1

• B. Ia2

• C. Ib1

• D. Ib2

• E. IIa

Answer: C

Question 3:

Choose a true statement about cervical cancer:

• A. Adenocarcinoma has a worse prognosis than squamous cell carcinoma.

• B. Stage I cancer has no lymph node involvement.

• C. Invasive form is the most common clinical presentation.

• D. The characteristic of stage IIa is that it has invaded the cervix but not the vagina.

• E. The most common clinical symptom is bloody vaginal discharge.

Answer: A

Question 4:

Among the following factors, which one is considered most relevant to cervical intraepithelial neoplasia?

• A. Human Papilloma virus (HPV) 6, 11

• B. HPV 16, 18

• C. Herpes simplex group 1

• D. Early intercourse under 17 years old

• E. Syphilis

Answer: B

Question 5:

The location of neoplasia in the cervical epithelium is:

• A. The boundary between squamous epithelium and columnar epithelium.

• B. Below the Nabothian cysts in the cervix.

• C. Glandular epithelium of the cervical canal.

• D. Squamous epithelium of the external os.

• E. The transformation zone in the cervix.

Answer: E

Question 6:

Choose the INCORRECT statement regarding cervical intraepithelial neoplasia:

• A. A cervical intraepithelial neoplasia can be caused by multiple HPV types.

• B. It can be screened by the Pap smear method.

• C. All cervical intraepithelial neoplasia lesions will eventually progress to cervical cancer.

• D. Cervical colposcopy is an indispensable tool for diagnosing cervical intraepithelial neoplasia.

• E. In most cases, conservative treatment is sufficient.

Answer: C

Question 7:

Regarding the FIGO classification of cervical cancer, choose the incorrect statement:

• A. Always used

• B. TNM classification is preferred

• C. It is based only on clinical examination

• D. Stage O is carcinoma in situ, cancer cells have not spread to the stroma and have not broken the basement membrane

Answer: B

Question 8:

The following prognostic factors in cervical cancer are all true, EXCEPT:

• A. Dependent on the patient’s age

• B. Dependent on FIGO stage

• C. Dependent on tumor size

• D. Dependent on lymph node spread

Answer: A

Question 9:

In the treatment of stage IIa cervical cancer, the following method is NOT used:

• A. Preoperative radiation therapy

• B. Radical hysterectomy + lymph node dissection

• C. Postoperative radiation therapy

• D. Chemotherapy alone

Answer: D

Question 10:

The following virus is a high risk in cervical cancer:

• A. CMV

• B. Herpes type 1 (HSV 1)

• C. HSV 2

• D. HPV type 16

Answer: D

Question 11:

Regarding the characteristics of stage IIa cervical cancer, choose the most correct statement:

• A. The tumor spreads to the vagina or broad ligament but not to the pelvic wall

• B. The tumor spreads to the vagina or broad ligament but not to the lower 1/3 of the vagina

• C. The tumor spreads not to the lower 1/3 of the vagina or broad ligament but not to the pelvic wall

• D. The tumor spreads to the lower 1/3 of the vagina or broad ligament but not to the pelvic wall

Answer: C

Question 12:

Which of the following is NOT a risk factor for cervical cancer?

• A. Early puberty

• B. Long-standing cervical lesions, not treated thoroughly

• C. Having sexual intercourse at a very young age and with multiple partners

• D. HPV infection

Answer: A

Question 13:

According to the FIGO clinical staging of cervical cancer, stage 0 is:

• A. Cancer that has just invaded the basement membrane

• B. Carcinoma in situ

• C. Cancer confined to the cervix

• D. Cancer that has invaded but not spread to the pelvic wall

Answer: B

Question 14:

To definitively diagnose invasive cervical cancer, it is necessary to:

• A. Cervical cytology (Pap’smear)

• B. Schiller’s test

• C. Cervical colposcopy

• D. Cervical biopsy

Answer: D

Question 15:

To prevent cervical cancer, it is necessary to guide the community on the following issues, EXCEPT:

• A. Women’s hygiene, avoid genital inflammation

• B. Sex education, healthy sexual activity

• C. Regular ultrasound

• D. Regular gynecological examinations / Guided childbirth

Answer: C

Question 16:

Cervical conization treatment is indicated in which of the following cases?

• A. Cervical cancer in pregnant women

• B. Stage 0 cervical cancer in young women

• C. When the cancer lesion on microscopy only invades the basement membrane < 10 mm

• D. Cervical adenocarcinoma

Answer: B

Question 17:

CIN lesions in the cervix can be identified through:

• A. Cervical colposcopy

• B. Pathological/histological examination

• C. Biochemical/hematological testing

• D. Clinical examination

Answer: B

Question 18:

CIN III lesion in the cervix is a dysplasia:

• A. Dysplasia < 1/3 of the epithelial layer

• B. Dysplasia < 1/2 of the epithelial layer

• C. Dysplasia < 2/3 of the epithelial layer

• D. Dysplasia > 2/3 of the epithelial layer

Answer: D

Question 19:

Which of the following is NOT a high-risk factor for CIN- cervical precancerous lesions?

• A. Alcoholism

• B. Smoking

• C. HPV infection

• D. HIV infection

Answer: A

Question 20:

The characteristic clinical symptom of CIN lesions in the cervix is:

• A. Vaginal discharge

• B. Cervical inflammation, condylomata

• C. Cervical ectropion

• D. All of A, B, C are incorrect

Answer: D

Question 21:

When clinically suspecting cervical precancerous lesions, the initial investigations to be performed are:

• A. Cervical colposcopy

• B. Cervical cytology/Pap’smear

• C. Cervical biopsy

• D. Only A, B are correct

Answer: D

Question 22:

Which of the following factors are favorable for CIN lesions in the cervix:

• A. Sexual activity from a very young age

• B. Having multiple sexual partners

• C. Smoking

• D. All of A, B, C are correct

Answer: D

Question 23:

Which of the following factors is favorable for CIN lesions in the cervix?

• A. Multiparity

• B. Preterm birth

• C. Postterm birth

• D. Childbirth with eclampsia

Answer: A

Question 24:

CIN is a lesion characterized by:

• A. Cervical ectropion

• B. Dysplasia of cervical epithelial cells

• C. Degree of cancer cell invasion

• D. Degree of cervical inflammation

Answer: B

Question 25:

When performing a routine gynecological examination, a Pap’smear should be performed to:

• A. Distinguish the type of bacteria causing cervical vaginitis

• B. Assess the degree of cervical inflammation

• C. Detect the presence of cervical cancer cells

• D. Assess the degree of cervical ectropion

Answer: C

Question 26:

To accurately diagnose cervical cancer, it is necessary to:

• A. Perform a Pap’smear

• B. Cervical biopsy

• C. Cervical colposcopy

• D. Ultrasound combined with endometrial curettage

Answer: B

Question 27:

To detect cervical cancer early, during routine gynecological examinations, it is necessary to pay attention to:

• A. Transvaginal ultrasound and cervical colposcopy

• B. Cervical colposcopy and HPV test

• C. Cervical colposcopy and Pap’smear

• D. Cervical colposcopy and Schiller’s test

Answer: C

Question 28:

Which of the following statements is NOT true regarding the risk factors for cervical cancer?

• A. Multiparity (over 5 children)

• B. Early and complex sexual activity

• C. Age 20-30 years old

• D. History of papillomavirus or herpes virus genital infections

• E. Impaired immune system

Answer: C

Question 29:

Invasive cervical cancer when

• A. Layers of cells appear stratified

• B. Cells show abnormal division, monstrous nuclei, divided nuclei

• C. Epithelial cells proliferate, destroying the basement membrane

• D. Internal tissue of the cervical canal is invaded

• E. C, D are correct

Answer: C

Question 30:

Cervical cancer often originates from

• A. Squamous epithelium

• B. Columnar epithelium

• C. Transformation zone

• D. From the uterine body down

• E. A,B,C,D are correct.

Answer: C

Question 31:

Cervical cancer often metastasizes along:

• A. Lymphatics

• B. Veins

• C. Adjacent connective tissue

• D. On the surface of the genitals

• E. A,B,C,D are correct

Answer: E

Question 32:

Purpose of vaginal cytology (Papanicolaou):

• A. To rule out cervical cancer

• B. To detect pathogenic bacteria

• C. Evaluate cervical injury

• D. To detect the presence of cancer cells

• E. If group III cells are present, there is a presence of cancer cells

Answer: D

Question 33:

Purpose of cervical colposcopy:

• A. To definitively diagnose cervical cancer

• B. To diagnose the stage of cervical cancer

• C. To find the presence of cancer cells

• D. To rule out cervical cancer

• E. Allows us to see suspicious areas

Answer: E

Question 34:

To accurately and comprehensively diagnose cervical cancer, we need:

• A. Clinical symptoms and abdominal ultrasound

• B. Clinical symptoms and cervical colposcopy

• C. Ultrasound and cervical colposcopy

• D. Just do vaginal cytology

• E. Vaginal cytology, cervical colposcopy and biopsy

Answer: E

Question 35:

Choose the most correct statement about cervical cancer prognosis:

• A. Age of patient

• B. Adenocarcinoma or squamous epithelium

• C. Stage and size of the cancer

• D. Degree of bleeding

• E. Invasive cancer

Answer: C

Question 36:

According to the FIGO clinical staging of cervical cancer stage IIb

• A. Cancer is still confined to the cervix

• B. When cancer extends beyond the cervix to the upper 1/3 of the vagina

• C. When cancer spreads to the bladder

• D. When cancer spreads to the lower 1/3 of the vagina

• E. When cancer spreads to the upper 1/3 of the vagina and the base of the broad ligament

Answer: E

Question 37:

According to the FiGO clinical staging of cervical cancer stage IIa is:

• A. When cancer spreads to the upper 1/3 of the vagina but does not invade the base of the broad ligament

• B. When cancer spreads to the upper 1/3 of the vagina and has invaded the base of the broad ligament

• C. When cancer spreads to the bladder and rectum

• D. When cancer spreads to the lower 1/3 of the vagina but not to the pelvic wall

• E. When cancer spreads to the lower 1/3 of the vagina and has spread to the pelvic wall

Answer: A

Question 38:

Cervical carcinoma in situ

• A. Also known as cancer in situ

• B. Connective tissue invasion less than 3mm

• C. Only metastasize to 1-2 nodes along the internal iliac artery

• D. Need to be indicated for radical total hysterectomy

• E. A,D are correct

Answer: E

Question 39:

Cellular abnormalities in cervical carcinoma in situ

• A. Normal nuclear size

• B. Large nuclear size, unequal size

• C. Dense chromatin

• D. Maintain stratification

• E. B,C are correct

Answer: E

Question 40:

Invasive cervical cancer

• A. Squamous epithelium accounts for 90%, columnar epithelium accounts for 10%

• B. Squamous epithelium accounts for 95%, columnar epithelium accounts for 5%

• C. Called microinvasive cancer if the basement membrane is broken and the tumor is less than 5mm

• D. A,C are correct

• E. B,C are correct

Answer: D

Question 41:

Vaginal bleeding in cervical cancer

• A. Menorrhagia

• B. Hypermenorrhea

• C. Dysmenorrhea

• D. Abnormal vaginal bleeding between periods, after intercourse

• E. Oligomenorrhea

Answer: D

Question 42:

Preclinical lesions of cervical cancer, choose the most correct statement

• A. Cervical hypertrophy

• B. Deep ulcerative and infected lesions

• C. Atypical white areas

• D. Grape-like appearance

• E. C,D are correct

Answer: E

Question 43:

According to the FIGO clinical staging, cervical cancer has invaded one or both broad ligaments, the uterus is still mobile, classified in stage:

• A. I A

• B. IIB

• C. IIA

• D. IVA

• E. IIIB

Answer: C

Question 44:

Histologically, cervical epithelial dysplasia (CIN III) is diagnosed when the following criteria are met:

• A. Abnormal cells with loss of polarity.

• B. Presence of undifferentiated cells

• C. Abnormal cells occupy over 2/3 of the epithelial layer thickness.

• D. The basement membrane has been broken.

• E. Abnormal cells with increased cell division.

Answer: C

Question 45:

Among benign cervical lesions, the lesion that is easily confused with cervical cancer is:

• A. Cervical ectropion

• B. Polyp of the external cervical os

• C. Cervical tuberculosis

• D. Cervical endometriosis

• E. Cervical syphilis

Answer: B

Question 46:

Which of the following is NOT a common feature of cervical cancer:

• A. The most common type of cancer in Vietnam

• B. Usually occurs in the columnar epithelium of the cervix

• C. In the early reproductive stage, there are often no obvious clinical symptoms

• D. Mainly metastasizes via lymphatics

• E. Can be detected early with a simple test

Answer: A

Question 47:

Which of the following factors is NOT a risk factor for cervical cancer:

• A. Early puberty

• B. Genital Human papilloma (HPV) infection

• C. Starting sexual intercourse at a very young age

• D. Having multiple sexual partners

• E. Food lacking vitamin A, folic acid

Answer: E

Question 48:

Cervical epithelial dysplasia is commonly found in the age group:

• A. Under 20 years old

• B. 20 – 40 years old

• C. 40 – 50 years old

• D. 50 – 60 years old

• E. Over 60 years old

Answer: E

Question 49:

Risk factors for cervical epithelial dysplasia and cancer are:

• A. Early pregnancy and multiparity

• B. Closely related to sexually transmitted diseases (STDs)

• C. Uterine endometriosis

• D. Impaired immunity

• E. Related to geographical conditions, race, poor socioeconomic conditions

Answer: B

Question 50:

Risk factors for cervical epithelial dysplasia and cancer are:

• A. Starting sexual intercourse under 17 years old

• B. Women with multiple sexual partners or husbands who have sexual relations with prostitutes

• C. Long-term use of progesterone-based contraceptives

• D. Genital Human papilloma (HPV) infection

• E. Genital Herpes simplex type II (HSV2) infection

Answer: B

Question 51:

The deciding factor in diagnosing invasive cervical cancer is:

• A. Abnormal bleeding

• B. Foul vaginal discharge

• C. Cervical condylomata, stiffness or ulceration

• D. Pap 4 or Pap 5

• E. Basement membrane rupture on microscopic image

Answer: E

Question 52:

The common location of cervical epithelial dysplasia is:

• A. Glandular columnar epithelium of the uterus

• B. Stratified squamous epithelium of the external os

• C. The boundary between the internal and external os

• D. Abnormal regeneration zone of ectropion

• E. The area with metaplastic lesions

Answer: C

Question 53:

Choose the correct answer: Column 1 because Column 2 All stages of cervical cancer are treated with surgery it removes all cancer tissue

• A. Column 1 is correct, Column 2 is correct and Column 2 explains Column 1

• B. Column 1 is correct, Column 2 is correct and Column 2 does not explain Column 1

• C. Column 1 is correct, Column 2 is incorrect

• D. Column 1 is incorrect, Column 2 is correct

• E. Column 1 is incorrect, Column 2 is incorrect

Answer: A

Question 54:

All the following statements comparing adenocarcinoma of the cervix and squamous cell carcinoma of the cervix are correct, EXCEPT:

• A. Adenocarcinoma is less common.

• B. Adenocarcinoma is more common in younger people.

• C. Adenocarcinoma also has a condylomatous form, an ulcerative form like squamous cell carcinoma.

• D. Columnar carcinoma is less sensitive to radiation.

Answer: C

Question 55:

Stage III cervical cancer has the following characteristics:

• A. Cancer has invaded the bladder floor.

• B. Cancer has invaded the lower 1/3 of the vagina but not the pelvic wall.

• C. Cancer has invaded the uterus but not the pelvic wall.

• D. Cancer has invaded the uterus and spread to the pelvic wall.

Answer: D

Question 56:

The characteristics of stage IIb cervical cancer are:

• A. Confined to the cervix but has invaded some of the stroma.

• B. Extends beyond the cervix, to the uterus, but the uterus is still mobile.

• C. Extends beyond the cervix, to the pelvic wall, but has not spread to the lower 1/3 of the vagina.

• D. Has spread to the pelvic wall and invaded the upper 1/3 of the vagina.

Answer: B

Question 57:

Cervical conization to treat cervical cancer for the case:

• A. Cervical cancer in pregnant women.

• B. In situ cervical cancer in young women.

• C. Cervical cancer remaining on the cervix after partial hysterectomy.

• D. When microscopic cancer lesion only invades the basement membrane < 5 mm.

Answer: B

Question 58:

The following regarding cervical cancer prognosis is correct:

• A. If detected and treated at stage 0, the 5-year survival rate is 100%.

• B. The 5-year survival rate for stage 1 cancer is 40- 60%.

• C. The 5-year survival rate for stage 2 cancer is 30%.

• D. The 5-year survival rate for stage III cancer is 20%.

Answer: A

Question 59:

Regularly performing vaginal cytology in women aged 30-40 according to the schedule:

• A. Every month.

• B. Every 6 months.

• C. Every 12 months to 18 months.

• D. Every 5 years.

Answer: B

Question 60:

The decisive test for diagnosing typical cervical cancer is:

• A. Cervical colposcopy.

• B. Vaginal cytology.

• C. Cervical biopsy.

• D. Speculum placement to observe the cervix.

Answer: C

Question 61:

Diagnose invasive cervical cancer, typical, based on the following symptoms, EXCEPT:

• A. Abnormal bleeding.

• B. Excessive, foul-smelling vaginal discharge, mixed with blood and pus.

• C. Lower abdominal pain.

• D. In postmenopausal patients.

Answer: D

Question 62:

Cervical conization treatment is indicated in which of the following cases:

• A. Cervical cancer in pregnant women.

• B. Stage 0 cervical cancer in young women.

• C. When microscopic cancer lesion only invades the basement membrane < 10 mm.

• D. Cervical adenocarcinoma.

Answer: B

Question 63:

The biopsy specimen is acceptable, should be taken from the transition zone between the two types of epithelium and suspicious areas.

• A. Correct

• B. Incorrect

Answer: A

Question 64:

To differentiate endometriosis from cervical cancer, histopathological examination is necessary.

• A. Correct

• B. Incorrect

Answer: A

Question 65:

Management of cervical epithelial dysplasia is:

• A. Cervical electrocautery for mild dysplasia (CIN I) if it does not resolve spontaneously after 6 months of follow-up

• B. Cervical electrocautery or conization for moderate dysplasia (CIN II)

• C. Severe dysplasia of the external os (CIN III) must have a total hysterectomy, even if the patient is young

• C. After treatment with cervical electrocautery or conization, it is necessary to continue monitoring cervical vaginal cytology

• D. After treatment, it is possible to use combined oral contraceptives

Answer: D/D/S/D/S

Question 66:

According to the FIGO clinical staging of cervical cancer, stage III is:

• A. Cancer has spread to the bladder floor

• B. Cancer has spread to the lower 1/3 of the vagina, but not to the iliac crest

• C. Cancer has spread to the broad ligament but not to the iliac crest

• D. Cancer has spread to the broad ligament and to the iliac crest

• E. Distant lymph node metastasis

Answer: S/D/D/D/S

Question 67:

Call cervical epithelial carcinoma in situ (Cancer in situ or stage O) on microscopic images on cervical biopsy specimens, we see:

• A. Squamous epithelial hyperplasia

• B. Severe glandular columnar epithelial hyperplasia

• C. Severe glandular columnar epithelial dysplasia

• D. Severe squamous epithelial dysplasia

• E. The basement membrane of the cells has not been broken

Answer: S/S/D/D/D

Question 68:

Management of stage IIB cervical cancer is:

• A. Total hysterectomy and bilateral adnexectomy

• B. Wertheim-Meigs surgery + postoperative radiotherapy

• C. Radiotherapy + Wertheim-Meigs surgery + postoperative radiotherapy

• D. Chemotherapy alone

• E. Radiotherapy alone

Answer: S/D/D/S/S

Question 69:

The 5-year survival rate for cervical cancer is:

• A. 100% if treated at stage O

• B. 90% if treated at stage I

• C. 40-60% if treated at stage II

• D. 15% if treated at stage III

• E. Under 10% if treated at stage IV

Answer: S/D/S/S/D

Question 70:

Cervical conization treatment is indicated in the following cases:

• A. Cervical cancer in pregnant women

• B. In situ cervical cancer in young people

• C. Cervical cancer remaining on the cervix after partial hysterectomy

• D. Cancer lesion invades the basement membrane < 5 mm

• E. Cervical adenocarcinoma

Answer: S/D/S/D/S

Question 71:

Management of stage III, IV cervical cancer is:

• A. Radiotherapy alone

• B. Radiotherapy + Wertheim-Meigs surgery

• C. Wertheim-Meigs surgery + postoperative radiation

• D. Chemotherapy alone

• E. Uterine-vaginal radium placement

Answer: S/D/D/S/D

Question 72:

Obvious cervical cancer lesions will …………..(not stain)………….. when Lugol’s solution is applied (Schiller’s test).

Answer: 1

Question 73:

Cervical carcinoma in situ in young women who still have childbearing desires can be treated with ……………………..(1)….(conization)……………………. or ………………………(2)………(cervical amputation)……………….

Answer: 1

Question 74:

When applying 3% acetic acid, dysplastic lesions will have a …..(1)………(white opaque)….., punctate or ………….(2)………..(mosaic)……. appearance. II. Understanding Level Questions

Answer: 1

Question 75:

The primary role of CT scan or MRI in diagnosing cervical cancer is:

• A. Accurately determine the extent of cervical cancer spread.

• B. Assess whether the kidney is hydronephrotic due to ureteral compression?

• C. Evaluate for pelvic lymph node metastasis?

• D. Determine if the bladder is invaded.

• E. Help to differentiate from other solid tumors in the cervix.

Answer: C

Question 76:

Appropriate surgical treatment for a case of stage Ib cervical cancer in a young woman includes the following parts, EXCEPT:

• A. Radical total hysterectomy.

• B. Bilateral adnexectomy.

• C. Partial vaginal resection.

• D. Removal of uterosacral ligaments and vesicouterine ligaments.

• E. Bilateral pelvic lymph node dissection.

Answer: B

Question 77:

The most appropriate treatment for a case of cervical carcinoma in situ and pregnancy (patient has not had enough children) is:

• A. Wait for the pregnancy to reach term, deliver naturally, and perform surgery 6-8 weeks after delivery.

• B. Wait for the pregnancy to reach term, perform a cesarean section, and then radiotherapy.

• C. Wait for the fetus to reach viability (32-34 weeks), perform a cesarean section, and then perform a total hysterectomy.

• D. If the fetus is < 10 weeks: perform radiotherapy immediately upon diagnosis.

• E. If the fetus is < 20 weeks: perform en bloc hysterectomy.

Answer: A

Question 78:

Which of the following signs allows the diagnosis of HPV infection:

• A. Presence of “clue cells” in vaginal smears.

• B. Presence of giant cells with a halo around the nucleus on cervical smears.

• C. Presence of punctate lesions on cervical colposcopy.

• D. Condyloma-like lesions on the cervix on speculum examination.

• E. Areas that do not stain dark brown on the cervix when performing the Lugol test.

Answer: B