Cervical Cancer Quiz:

2014. Which of the following is NOT a cofactor in causing cervical cancer:

A. Smoking.

B. Early sexual activity.

C. Having multiple sexual partners.

D. Early menarche.

E. Immunodeficiency.

Answer: D.

2015. Cervical cancer with clinical lesions confined to the cervix, lesion size < 4cm is classified as what stage?

A. Ia1.

B. Ia2.

C. Ib1.

D. Ib2.

E. IIa.

Answer: C.

2016. Choose the correct statement about cervical cancer:

A. Adenocarcinoma has a worse prognosis than squamous cell carcinoma.

B. Stage I cancer has no lymph node involvement.

C. Invasive form is the most common clinical presentation.

D. The characteristic of stage IIa is that it has invaded the cervix but not yet reached the vagina.

E. The most common clinical symptom is bloody vaginal discharge.

Answer: A.

2017. Among the following factors, which is considered to be most closely related to cervical intraepithelial neoplasia:

A. Human Papilloma virus (HPV) 6, 11.

B. HPV 16, 18.

C. Herpes simplex group 1.

D. Early sexual intercourse under 17 years old.

E. Syphilis.

Answer: B.

2018. The location of the appearance of neoplasia in the cervical epithelium is:

A. The boundary between squamous epithelium and columnar epithelium.

B. Below the Nabothian cysts in the cervix.

C. The glandular epithelium of the cervical canal.

D. The squamous epithelium of the ectocervix.

E. The transformation zone in the cervix.

Answer: E.

2019. Choose the FALSE statement, regarding cervical intraepithelial neoplasia:

A. One cervical intraepithelial neoplasia can be caused by multiple types of HPV.

B. It can be screened by the vaginal smear method (Pap smear).

C. All cervical intraepithelial neoplasia lesions will eventually progress to cervical cancer.

D. Colposcopy is an indispensable tool for diagnosing cervical intraepithelial neoplasia.

E. In most cases, conservative treatment is sufficient.

Answer: C.

2020. Regarding the FIGO classification of cervical cancer, choose the wrong statement:

A. Always used

B. TNM classification is preferred

C. It is only based on clinical examination

D. Stage O is carcinoma in situ, cancer cells have not invaded the stroma and have not broken through the basement membrane

Answer: B.

2021. The following prognostic factors in cervical cancer are all correct, EXCEPT:

A. Depends on the age of the patient

B. Depends on the stage according to FIGO

C. Depends on the tumor size

D. Depends on lymph node spread

Answer: A.

2022. In the treatment of stage IIa cervical cancer, the following method is not used:

A. Preoperative radiotherapy

B. Radical hysterectomy + lymph node dissection

C. Postoperative radiotherapy

D. Chemotherapy alone

Answer: D.

2023. The following virus is a high risk in cervical cancer:

A. CMV

B. Herpes type 1 (HSV 1)

C. HSV 2

D. HPV type 16

Answer: D.

2024. Regarding the characteristics of stage IIa cervical cancer, choose the most accurate statement:

A. Tumor extends to vagina or broad ligament but not to the pelvic wall

B. Tumor extends to vagina or broad ligament but not to the lower 1/3 of vagina

C. Tumor extends not to the lower 1/3 of vagina or broad ligament but not to the pelvic wall

D. Tumor extends to the lower 1/3 of vagina or broad ligament but not to the pelvic wall

Answer: C.

2025. Which of the following is NOT a risk factor for cervical cancer?

A. Early puberty

B. Persistent cervical lesions, not completely treated

C. Having sex at a very young age and having sex with many people

D. HPV infection

Answer: A.

2026. According to the FIGO clinical staging of cervical cancer, stage 0 is:

A. Cancer that has just invaded through the basement membrane

B. Carcinoma in situ

C. Cancer confined to the cervix

D. Cancer that has not invaded the pelvic wall

Answer: B.

2027. To definitively diagnose invasive cervical cancer, you need to:

A. Cervical cytology (Pap’smear)

B. Schiller test

C. Colposcopy

D. Cervical biopsy

Answer: D.

2028. To prevent cervical cancer, it is necessary to guide the community on the following issues, EXCEPT:

A. Female hygiene, avoid genital infections

B. Sex education, healthy sexual activity

C. Regular ultrasound

D. Regular gynecological checkups / Guided childbirth

Answer: C.

2029. Treatment of cervical cancer by cervical conization is indicated in which of the following cases:

A. Cervical cancer in pregnant women

B. Stage 0 cervical cancer in young women

C. When on microscopy, the cancerous lesion only invades the basement membrane < 10mm

D. Cervical adenocarcinoma

Answer: B.

2030. CIN lesions in the cervix can be identified through:

A. Colposcopy

B. Pathology / histology

C. Biochemical / hematological tests

D. Clinical examination

Answer: B.

2031. CIN III lesions in the cervix are dysplastic lesions:

A. Dysplasia < 1/3 of the epithelial layer

B. Dysplasia < 1/2 of the epithelial layer

C. Dysplasia < 2/3 of the epithelial layer

D. Dysplasia > 2/3 of the epithelial layer

Answer: D.

2032. Which of the following is NOT a high-risk factor for pre-cancerous CIN lesions in the cervix:

A. Alcoholism

B. Smoking

C. HPV infection

D. HIV infection

Answer: A.

2033. The characteristic clinical symptom of CIN lesions in the cervix is:

A. Vaginal discharge

B. Cervical inflammation, condyloma

C. Cervical ectopy

D. All of A, B, C are incorrect

Answer: D.

2034. When clinically suspecting pre-cancerous lesions of the cervix, the first examinations to be performed are:

A. Colposcopy

B. Cervical cytology / Pap’smear

C. Cervical biopsy

D. Only A, B are correct

Answer: D.

2035. Which of the following factors are favorable for CIN lesions in the cervix:

A. Sexual activity from a very young age

B. Having multiple sexual partners

C. Smoking

D. All of A, B, C are correct

Answer: D.

2036. Which of the following factors are favorable for CIN lesions in the cervix

A. Giving birth many times

B. Premature birth

C. Giving birth to an overdue baby

D. Giving birth with eclampsia

Answer: A.

2037. CIN is a lesion characterized by:

A. Cervical ectopy

B. Dysplasia of the cervical epithelium

C. Degree of cancer cell invasion

D. Degree of cervical inflammation

Answer: B.

2038. When doing routine gynecological examinations, it is necessary to perform Pap’smear cervical vaginal cytology to:

A. Differentiate the types of bacteria that cause cervical vaginal inflammation

B. Assess the degree of cervical inflammation

C. Detect the presence of cervical cancer cells

D. Evaluate the degree of cervical ectopy

Answer: C.

2039. To make a definitive diagnosis of cervical cancer, you need to:

A. Perform Pap’smear cervical vaginal cytology

B. Cervical biopsy

C. Colposcopy

D. Ultrasound combined with curettage and endometrial biopsy

Answer: B.

2040. To detect cervical cancer early, when performing routine gynecological examinations, it is necessary to pay attention to:

A. Vaginal probe ultrasound and colposcopy

B. Colposcopy and HPV test

C. Colposcopy and Pap’smear

D. Colposcopy and Schiller test

Answer: C.

2041. Which of the following statements is NOT true about the risk factors for cervical cancer?

A. Giving birth many times (over 5 children)

B. Early and complex sexual activity

C. Age from 20-30 years old

D. History of papillomavirus or herpes virus genital infections

E. Immune system decline

Answer: C.

2042. Invasive cervical cancer when

A. The cell layers appear stratified

B. Cells appear atypical with abnormal nuclei, nuclear division

C. The epithelial cells proliferate, destroying the basement membrane

D. Tissues inside the cervical canal are invaded

E. C, D are correct

Answer: C.

2043. Cervical cancer usually originates from

A. Squamous epithelium

B. Columnar epithelium

C. Transformation zone

D. From the uterine body down

E. A,B,C,D are correct.

Answer: C.

2044. Cervical cancer usually metastasizes through:

A. Lymphatic pathways

B. Venous pathways

C. Adjacent connective tissue

D. Along the surface of the reproductive organs

E. A,B,C,D are correct

Answer: A.

2045. The purpose of vaginal cytology (Papanicolaou):

A. To rule out cervical cancer

B. To detect pathogenic bacteria

C. Assess cervical damage

D. To detect the presence of cancer cells

E. If group III cells are present, there is the presence of cancer cells

Answer: D.

2046. The purpose of colposcopy:

A. To make a definitive diagnosis of cervical cancer

B. To diagnose the stage of cervical cancer

C. To find the presence of cancer cells

D. To rule out cervical cancer

E. Allows us to see the suspicious area

Answer: E.

2047. To make an accurate and complete diagnosis of cervical cancer, we need to:

A. Clinical symptoms and abdominal ultrasound

B. Clinical symptoms and colposcopy

C. Ultrasound and colposcopy

D. Just do vaginal cytology

E. Vaginal cytology, colposcopy and biopsy

Answer: E.

2048. Choose the most accurate statement about the prognosis of cervical cancer:

A. Age of the patient

B. Adenocarcinoma or squamous cell carcinoma

C. Stage and size of the cancer

D. Degree of bleeding

E. Invasive cancer

Answer: C.

2049. According to the FIGO clinical staging of cervical cancer stage II b

A. Cancer is still confined to the cervix

B. When cancer extends beyond the cervix to the upper 1/3 of the vagina

C. When cancer spreads to the bladder

D. When cancer spreads to the lower 1/3 of the vagina

E. When cancer spreads to the upper 1/3 of the vagina and the broad ligament base

Answer: E.

2050. According to the FiGO clinical staging of cervical cancer, stage II a is:

A. When cancer spreads to the upper 1/3 of the vagina but does not invade the broad ligament base

B. When cancer spreads to the upper 1/3 of the vagina and has invaded the broad ligament base

C. When cancer spreads to the bladder and rectum

D. When cancer spreads to the lower 1/3 of the vagina but not to the pelvic wall

E. When cancer spreads to the lower 1/3 of the vagina and has spread to the pelvic wall

Answer: A.

2051. Cervical carcinoma in situ

A. Also known as in situ cancer

B. Connective tissue invasion under 3mm

C. Only metastasis in 1-2 lymph nodes along the internal iliac artery

D. Requires radical hysterectomy

E. A,D are correct

Answer: A.

2052. Cellular abnormalities in cervical carcinoma in situ

A. Normal nuclear size

B. Large, uneven nuclear size

C. Dense chromatin

D. Maintain stratification

E. B,C are correct

Answer: E.

2053. Invasive cervical cancer

A. Squamous cell carcinoma accounts for 90%, adenocarcinoma accounts for 10%

B. Squamous cell carcinoma accounts for 95%, adenocarcinoma accounts for 5%

C. It is called microinvasive cancer if the basement membrane is broken and the tumor is less than 5mm in size

D. A,C are correct

E. B,C are correct

Answer: E.

2054. Vaginal bleeding in cervical cancer

A. Menorrhagia

B. Hypermenorrhea

C. Dysmenorrhea

D. Abnormal vaginal bleeding between periods, after intercourse

E. Oligomenorrhea

Answer: D.

2055. Preclinical lesions of cervical cancer, choose the most accurate statement

A. Cervical hypertrophy

B. Deep ulcerative lesions and infection

C. Atypical white area

D. Grape-like appearance

E. C,D are correct

Answer: C.

2056. According to the FIGO clinical staging, cervical cancer has invaded one or both broad ligaments, the uterus is still mobile, classified as stage:

A. I A

B. IIB

C. IIA

D. IVA

E. IIIB

Answer: C.

2057. Histologically, cervical dysplasia is considered severe cervical epithelial dysplasia (CIN III) when the following criteria are met:

A. Cellular abnormalities accompanied by loss of polarity.

B. Presence of undifferentiated cells

C. Abnormal cells account for over 2/3 of the epithelial layer thickness.

D. The basement membrane has been broken.

E. Abnormal cells accompanied by increased cell division.

Answer: C.

2058. Among benign cervical lesions, the lesion most easily confused with cervical cancer is:

A. Cervical ectopy

B. Polyp of the cervical os

C. Cervical tuberculosis

D. Cervical endometriosis

E. Cervical syphilis

Answer: B.

2059. Which of the following is NOT a common feature of cervical cancer:

A. The most common type of cancer in Vietnam

B. Often appears in the columnar epithelium of the cervix

C. In the reproductive period, early stages often have no obvious clinical symptoms

D. Primarily metastasize through the lymphatic system

E. Can be detected early with a simple test

Answer: A.

2060. Which of the following factors is NOT a dangerous factor causing cervical cancer:

A. Early puberty

B. Genital Human papilloma (HPV) infection

C. Starting sexual intercourse at a very young age

D. Having many sexual partners

E. Lack of vitamins A, folic acid in the diet

Answer: E.

2061. Cervical dysplasia is often seen in people:

A. Under 20 years old

B. From 20 – 40 years old

C. From 40 – 50 years old

D. From 50 – 60 years old

E. Over 60 years old

Answer: E.

2062. Risk factors for cervical dysplasia and cancer are:

A. Early pregnancy and multiple pregnancies

B. Closely related to sexually transmitted diseases (STD)

C. Uterine endometriosis

D. Immune deficiency

E. Related to geographical conditions, race, low socioeconomic conditions

Answer: B.

2063. Risk factors for cervical dysplasia and cancer are:

A. Starting sexual intercourse under 17 years old

B. Women with multiple sexual partners or husbands who have sex with prostitutes

C. Long-term use of Progesterone-type oral contraceptives

D. Genital Human papilloma (HPV) infection

E. Genital Herpes simplex type II (HSV2) infection

Answer: C.

2064. The decisive factor in diagnosing invasive cervical cancer is:

A. Abnormal bleeding

B. Foul discharge

C. Cervical condyloma, hardening or ulceration

D. Pap 4 or Pap 5

E. Basement membrane cell destruction on microscopy

Answer: E.

2065. The location where cervical dysplasia is often found is:

A. Glandular columnar epithelium of the uterus

B. Stratified squamous epithelium of the ectocervix

C. The boundary between the endocervix and ectocervix

D. The area of abnormal regeneration of the transformation zone

E. The area with metaplastic lesions

Answer: C.

2066. Choose the correct answer: Column 1 because Column 2 All stages of cervical cancer are treated with surgery it completely removes the cancerous tissue

A. Column 1 is correct, Column 2 is correct and Column 2 explains Column 1

B. Column 1 is correct, Column 2 is correct and Column 2 does not explain Column 1

C. Column 1 is correct, Column 2 is incorrect

D. Column 1 is incorrect, Column 2 is correct

E. Column 1 is incorrect, Column 2 is incorrect

Answer: A.

2067. All of the following statements comparing cervical adenocarcinoma and squamous cell carcinoma are correct, EXCEPT:

A. Adenocarcinoma is less common.

B. Adenocarcinoma is more common in younger women.

C. Adenocarcinoma also has condyloma, ulcerative forms like squamous cell carcinoma.

D. Adenocarcinoma is less sensitive to radiation.

Answer: C.

2068. Stage III cervical cancer is characterized by:

A. Cancer has invaded the bladder base.

B. Cancer has invaded the lower 1/3 of the vagina but not the pelvic wall.

C. Cancer has invaded the uterus but not the pelvic wall.

D. Cancer has invaded the uterus and spread to the pelvic wall.

Answer: D.

2069. The characteristic of stage IIb cervical cancer is:

A. Confined to the cervix but has invaded some stroma.

B. Spreads out of the cervix, to the uterus but the uterus is still mobile.

C. Spreads out of the cervix, to the pelvic wall but not to the lower 1/3 of the vagina.

D. Has spread to the pelvic wall and invaded the upper 1/3 of the vagina.

Answer: B.

2070. Cervical conization to treat cervical cancer for:

A. Cervical cancer in pregnant women.

B. In situ cervical cancer in young women.

C. Cervical cancer on the remaining cervix after partial hysterectomy.

D. When on microscopy, the cancerous lesion only invades the basement membrane < 5mm.

Answer: B.

2071. About the prognosis of cervical cancer is correct:

A. If detected and treated in stage 0, the 5-year survival rate is 100%.

B. The 5-year survival rate of stage 1 cancer is 40- 60%.

C. The 5-year survival rate of stage 2 cancer is 30%.

D. The 5-year survival rate of stage III cancer is 20 %.

Answer: A.

2072. Regularly performing vaginal smears in women aged 30 – 40 according to the schedule:

A. Every month.

B. Every 6 months.

C. Every 12 months to 18 months.

D. Every 5 years.

Answer: B.

2073. The test that is decisive in diagnosing typical cervical cancer is:

A. Colposcopy.

B. Performing vaginal cytology.

C. Cervical biopsy.

D. Placing a speculum to observe the cervix.

Answer: C.

2074. Diagnosis of typical invasive cervical cancer is based on the following symptoms, EXCEPT:

A. Abnormal bleeding.

B. Heavy, foul-smelling discharge, mixed with blood and pus.

C. Lower abdominal pain.

D. In postmenopausal women.

Answer: D.

2075. Treatment of cervical cancer by cervical conization is indicated in which of the following cases:

A. Cervical cancer in pregnant women.

B. Stage 0 cervical cancer in young women.

C. When on microscopy, the cancerous lesion only invades the basement membrane < 10mm.

D. Cervical adenocarcinoma.

Answer: B.

2076. Biopsy specimens are required to be taken from the transition zone between the two types of epithelium and the suspicious area.

A. True

B. False

Answer: A.

2077. To differentiate endometriosis from cervical cancer, histological examination is required.

A. True

B. False

Answer: A.

2078. Treatment of cervical dysplasia is:

A. Electrocautery of the cervix for mild dysplasia (CIN I) if it does not regress spontaneously after 6 months of follow-up

B. Electrocautery or cervical conization for moderate dysplasia (CIN II) follow-up

C. Severe cervical dysplasia (CIN III) must be treated with total hysterectomy even if the patient is young follow-up

C. After treatment with electrocautery or cervical conization, continue to follow-up with cervical vaginal cytology follow-up

D. After treatment, you can use combined oral contraceptives for contraception follow-up

Answer: A – True, B – True, C – False, D – True, E – False

2079. According to the FIGO clinical staging of cervical cancer, stage III is:

A. Cancer has spread to the bladder base follow-up

B. Cancer has spread to the lower 1/3 of the vaginal wall, but not to the iliac crest follow-up

C. Cancer has spread to the broad ligament but not to the iliac crest follow-up

D. Cancer has spread to the broad ligament and iliac crest follow-up

E. Distant lymph node metastasis follow-up

Answer: A – False, B – True, C – True, D – True, E – False

2080. Cervical intraepithelial neoplasia (Cancer in situ or stage O) on histological images on cervical biopsy specimens, we see:

A. Squamous epithelial hyperplasia follow-up

B. Severe glandular columnar epithelial hyperplasia follow-up

C. Severe glandular columnar epithelial dysplasia follow-up

D. Severe stratified squamous epithelial dysplasia follow-up

E. Basement membrane cells have not been broken follow-up

Answer: A – False, B – False, C – True, D – True, E – True

2081. Treatment of stage IIB cervical cancer is:

A. Total hysterectomy and two appendages follow-up

B. Wertheim-Meigs surgery + postoperative radiation therapy follow-up

C. Radiation therapy + Wertheim-Meigs surgery + postoperative radiation therapy follow-up

D. Chemotherapy alone follow-up

E. Radiation therapy alone follow-up

Answer: A – False, B – True, C – True, D – False, E – False

2082. The 5-year survival rate of cervical cancer is:

A. 100% if treated at stage O follow-up

B. 90% if treated at stage I follow-up

C. 40 – 60% if treated at stage II follow-up

D. 15% if treated at stage III follow-up

E. Under 10% if treated at stage IV follow-up

Answer: A – False, B – True, C – False, D – False, E – True

2083. Treatment of cervical cancer by cervical conization is indicated in the following cases:

A. Cervical cancer in pregnant women follow-up

B. In situ cervical cancer in young women follow-up

C. Cervical cancer on the remaining cervix after partial hysterectomy follow-up

D. Cancerous lesions invading the basement membrane < 5 mm follow-up

E. Cervical adenocarcinoma follow-up

Answer: A – False, B – True, C – False, D – True, E – False

2084. Treatment of stage III, IV cervical cancer is:

A. Radiation therapy alone follow-up

B. Radiation therapy + Wertheim-Meigs surgery follow-up

C. Wertheim-Meigs surgery + postoperative radiation therapy follow-up

D. Chemotherapy alone follow-up

E. Uterine – vaginal Radium placement follow-up

Answer: A – False, B – True, C – True, D – False, E – True

2085. Cervical cancer lesions clearly visible on clinical examination will not stain when Lugol’s solution is applied (Schiller’s test).

2086. Carcinoma in situ of the cervix in young women who still want to have children can be treated by conization or cervical amputation.

2087. When 3% acetic acid is applied, dysplastic lesions will have a white cloudy appearance, punctuate or mosaic pattern.

2088. The main role of CT scan or MRI in diagnosing cervical cancer is:

A. Accurately determine the extent of spread of cervical cancer.

B. Evaluate whether the kidney is hydronephrotic due to ureteral obstruction?

C. Evaluate for pelvic lymph node metastasis?

D. Determine whether the bladder is invaded.

E. Help differentiate from other solid tumors in the cervix.

Answer: C.

Cervical Cancer Quiz: