Cervical HSIL: Histological Images

Histological images reveal cervical HSIL with the following features:

• Stroma: Hemorrhage and infiltrating inflammatory cells (marked by circles).

• Basement membrane: The normal stratified squamous epithelium basement membrane of the cervix (pale pink) is marked by orange arrows.

• Dysplastic epithelium: Dysplastic epithelium is dark purple, with high cellular density, enlarged nuclei, hyperchromasia, and pleomorphism (marked by orange arrows).

• Cell axis: Cell axis is parallel to the imaginary basement membrane (marked by a straight line).

• Mitotic figures: Mitotic figures are observed (marked by orange arrows).

• Superficial cell layer: The superficial squamous cell layer is marked by orange arrows.

• Carcinoma in situ: Carcinoma in situ is recognized by surface cells with large, pleomorphic, hyperchromatic, and vertically oriented nuclei (marked by orange arrows).

Note:

• These features are only a part of the diagnosis of cervical HSIL.

• The final diagnosis must be made by a specialist based on laboratory results and clinical evaluation.