Lesson 5.7: Hemophilia and Von Willebrand Disease

1. Hemophilia:

• Bleeding commonly occurs: Before the age of 1 (B).

• Joint bleeding: 70-80% (B).

• Bleeding in muscles and soft tissues: 10-20% (A).

• Bleeding in the central nervous system: Less than 5% (A).

• Other bleeding: 5-10% (B).

2. Von Willebrand Disease:

• Characteristics:

• Prolonged bleeding time (A)

• Incomplete clot formation (B)

• Reduced factor 8 (C)

• Decreased platelet aggregation with Ristocetin (D)

• All of the above (E)

• Details:

• Bleeding time: Prolonged (B).

• Clot formation: Incomplete (B).

• Factor 8: Reduced (B).