The Metabolic Function of the Kidneys

The kidneys, besides their primary role in blood filtration and waste excretion, also participate in crucial metabolic processes within the body.

Carbohydrate Metabolism:

• The kidneys primarily carry out carbohydrate metabolism through the glycolytic pathway.

Lipid Metabolism:

• Leucithin undergoes dephosphorylation by glycerolphosphate.

• Ketonic substances are fully catabolized in the kidneys.

Protein Metabolism:

• The kidneys contain numerous deaminase enzymes, which generate alpha-keto acids and release NH3 in the form of NH4+.

Specific Metabolic Processes:

• The kidneys participate in the dehydration of creatine into creatinine.

• The kidneys catalyze the condensation reaction of benzoic acid with glycine to form hippuric acid.

In conclusion, the kidneys play a significant role in the metabolism of carbohydrates, lipids, proteins, and other specific metabolic processes, contributing to the maintenance of homeostasis in the body.